Publications
All published articles, reviews and book chapters are here
A ranking of the published articles by journal impact factors is here
2023
INPP5K controls the dynamic structure and signaling of wild type and mutated, leukemia-associated IL7 receptors.
Blood 141;1708-1717 (abstract )
Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment.
iScience 26; doi: 10.1016/j.isci.2023.106071 (abstract )
2022
INPP5E controls ciliary localization of phospholipids and odor response in olfactory sensory neurons.
J. Cell Sci. 135; doi: 10.1242/jcs.258364 (abstract )
2021
The phosphoinositide 5-phosphatase INPP5K: from gene structure to in vivo functions.
Adv. Biol. Regul. doi: 10.1016/j.jbior.2020.100760 (abstract )
Inositol-triphosphate 3-kinase B promotes calcium mobilization and the inflammatory activity of dendritic cells.
Sci. Signal. 14; doi: 10.1126/scisignal.aaz2120 (abstract )
2020
The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory role in Shh signaling.
Development doi: 10.1242/dev.183301 (abstract )
Altered chondrocyte differentiation, matrix mineralization and MEK-Erk1/2 signaling in an INPPL1 catalytic knock-out mouse model of opsismodysplasia.
Adv. Biol. Regul. doi: 10.1016/j.jbior.2019.100651. (abstract)
2019
Primary cilia signaling promotes axonal tract development and is disrupted in Joubert syndrome-related disorders models.
Dev. Cell 51; 759-774 (abstract )
2018
Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism.
PLOS Genetics 14; e1007195 (abstract)
2017
The lipid 5-phosphatase Ship2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins.
Kidney Int. 92; 125-139 (abstract)
Dynamic remodeling of membrane composition drives cell cycle through primary cilia excision.
Cell 168; 264-279 (abstract)
2015
Modulation of ciliary phosphoinositide content regulates trafficking and Sonic Hedgehog signaling output.
Dev. Cell 34; 338-350 (abstract)
Phosphoinositides regulate ciliary protein trafficking to modulate hedgehog signaling.
Dev. Cell 34; 400-409 (abstract)
2014
Rasa3 controls megakaryocyte Rap1 activation, integrin signaling and differentiation into proplatelet.
PLOS Genetics 10; e1004420 (abstract)
Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology.
Brain 137; 537-52 (abstract)
2011
Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, beta cell proliferation and mass.
Diabetes 60; 2076-85. (abstract)
2009
INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse.
Nature Genetics 41;1027-1031 (abstract)
Mutations in the inositol polyphosphate-5-phosphatase E gene link phosphatidylinositol signaling to the ciliopathies.
Nature Genetics 41;1032-1036 (abstract)
2008
Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis.
Proc. Natl Acad. Sci. USA 105;4739-4744 (abstract)
2007
Inositol 1,3,4,5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells.
Proc. Natl Acad. Sci. USA 104;13978-13983 (abstract)
Ins(1,3,4,5)P4 negatively regulates PtdIns(3,4,5)P3 signaling in neutrophils.
Immunity 27;453-467 (abstract)
2004
Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3.
J. Clin. Invest. 113;265-273 (abstract)
2003
Inositol 1,3,4,5-tetrakisphosphate is essential for normal T lymphocyte development.
Nature Immunol. 4;1136-1143 (abstract)
2002
The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man.
Diabetes 51;2012-2017 (abstract)
2001
The lipid phosphatase SHIP2 controls insulin sensitivity.
Nature 409;92-96 (abstract)
